DEFICIENCY OF VITAMIN A OF 6 MONTHS: EFFECT ON PROTEIN OXIDATION AND ITS CORRELATION WITH THE LIVER GLUCOSE LEVELS

AGÜERO R; VASQUEZ GOMEZ ME; RAZZETO G; OROZCO REINA A; DELLA VEDOVA MARIA CECILIA; ALVAREZ S; GIMENEZ MS

Congreso; XXXVI Reunión Anual de la Sociedad de Biologia de Cuyo; 2018

Sociedad de Biologia de Cuyo

The vitamin A (VA) is an essential nutrient for cell growth and differentiation. Previous work done in our laboratory has shownthat vitamin A deficiency modifies oxidative stress parameters and lipid metabolism in heart and aorta. Oxidative stress is theexposure of living tissue to various sources that produce a rupture of the balance between pro-oxidant factors and antioxidantmechanisms. This generates alterations in the structure-function relationship of any organ. The objective of this work was tostudy of the parameters of the oxidative stress, metabolism of lipids and glucose in liver of ratsvitamin A deficiency (VAD). Wedetermined reactive species to the tribarbituric acid (TBARS), carbonyls groups of proteins by ELISA, quantification of tissueand serum lipids and serum glucose by enzymatic assays using an autoanalyzer CB350i (Wiener Lab). Statistical analysis: Oneway Anova, tukey post test, regression and correlation analysis with Graphpad Prism. P