INVESTIGADORES
MASONE Diego Fernando
artículos
Título:
The SARS-CoV-2 mutation landscape is shaped before replication starts
Autor/es:
MASONE, DIEGO; SOLEDAD ALVAREZ, MARIA; POLO, LUIS MARIANO
Revista:
GENETICS AND MOLECULAR BIOLOGY
Editorial:
SOC BRASIL GENETICA
Referencias:
Año: 2023 vol. 46 p. 1 - 4
ISSN:
1415-4757
Resumen:
Mutation landscapes and signatures have been thoroughly studied in SARS-CoV-2. Here, we analyse those patterns and link their changes to the viral replication tissue in the respiratory tract. Surprisingly, a substantial difference in those patterns is observed in samples from vaccinated patients. Hence, we propose a model to explain where those mutations could originate during the replication cycle.
