Yeast species distribution in Neonatal Intensive Care Units in the northeast Argentina

GIUSIANO G; MANGIATERRA M; ROJAS F; GÓMEZ V

MYCOSES

WILEY-BLACKWELL PUBLISHING, INC

Lugar: ALEMANIA; Año: 2004 vol. 47 p. 300 - 303

0933-7407

The aim of this study was to determine the distribution and antifungal susceptibility profile of yeast species isolated from neonates in Neonatal Intensive Care Units (NICU) in northeast of Argentina. With this purpose 92 strains isolated from 25 blood stream cultures, 20 venous catheters, 23 suprapubic aspirations and 24 rectal swabs were studied. C. albicans and C. parapsilosis appeared with similar frequencies (36%) in blood stream isolates. C. parapsilosis (50%) was the most frequent catheters colonizer and C. tropicalis (54,2%) was the most frequent yeast associated with gastrointestinal tract colonization. C. krusei, C. glabrata and Trichosporon cutaneum appears with a very low frequency. A high rate of susceptibility to amphotericin B, fluconazole and itraconazole was observed. The variations in the epidemiology of fungal infections detected in neonates in NICU, as well as in antifungal resistance, emphasize the importance of performing a permanent surveillance to observe and to assess these variations.