INVESTIGADORES
GIUSIANO Gustavo Emilio
artículos
Título:
Infección por Candida auris en el catéter central de un paciente sin síntomas de sepsis
Autor/es:
CASTRO LA; ALVAREZ MI; ROJAS F; GIUSIANO G; SAN MARTÍN - MARTINEZ E
Revista:
COLOMBIA MéDICA
Editorial:
CORPORACION EDITORA MEDICA VALLE
Referencias:
Año: 2019 vol. 50 p. 293 - 298
Resumen:
Candida auris is an emerging yeast frequently reported as resistant to multipleantifungal drugs commonly used to treat Candida infections. This specie can colonize the patient?s skin and has great ability for producing outbreaks in hospitals. C. auris is phylogenetically related to other Candida species, can be misidentified using conventional biochemical or commercial methods and requires specific technology for its identification.We report the first isolate of C. auris in Cali, Colombia, from a central venouscatheter in a 37-year-old patient with rheumatoid arthritis and endocarditis who did not have symptoms of sepsis. The yeast was initially misidentified as C. haemulonii using the Phoenix system and subsequently identified as C. auris by matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry (MALDI-TOF MS). The broth microdilution method was used to determine the minimum inhibitory concentration; the isolate was susceptible to fluconazole, itraconazole, voriconazole and amphotericin B.This report contributes to knowledge of the epidemiology of C. auris infections in individuals with underlying disease and describes an isolate with a behavior different from what is usually reported.