Unexpected metal-free dehydrogenation of a Β-ketoester to a phenol using a recyclable oxoammonium salt

POLITANO, FABRIZIO; BRYDON, WILLIAM P.; NANDI, JYOTI; LEADBEATER, NICHOLAS E.

MolBank

MDPI AG

Lugar: Basel; Año: 2021 vol. 2021 p. 1 - 5

The conversion of ethyl 2-oxocyclohexanecarboxylate to ethyl salicylate using an oxoammonium salt is reported. The dehydrogenation reaction is operationally simple and compares favorably with previous literature examples for the same transformation and expands the scope of oxoammonium salts as reagents for oxidative functionalization processes.