INVESTIGADORES
DIAZ NIETO Cesar Horacio
artículos
Título:
Sterigmatocystin: A mycotoxin to be seriously considered
Autor/es:
DÍAZ NIETO, CÉSAR HORACIO; GRANERO, ADRIAN MARCELO; ZON, MARÍA ALICIA; FERNÁNDEZ, HÉCTOR
Revista:
FOOD AND CHEMICAL TOXICOLOGY
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Año: 2018 vol. 118 p. 460 - 470
ISSN:
0278-6915
Resumen:
Sterigmatocystin is a carcinogenic compound that affects several species of crops and several species of experimental animals. The sterigmatocystin biosynthetic pathway is the best known and most studied. The International Agency for Research on Cancer classifies sterigmatocystin in the Group 2B. Three groups of analytical methods to determine sterigmatocystin in food can be found: chromatographic, ELISA immunoassays and chemical sensors. In addition, sterigmatocystin is a precursor of aflatoxin B1 in those cases where cereals and/or food are contaminated with fungi capable of producing aflatoxins. Chemical structures of sterigmatocystin and aflatoxin B1 are similar. These mycotoxins are pathogens of animals and cereals, producing a major economic impact on biotechnology and agricultural and food industries.This review summarizes different aspects related to sterigmatocystin such as its biosynthesis, toxicological studies and analytical methods for its determination.
