Phylemon: a suite of web tools for molecular evolution, phylogenetics and phylogenomics

TÁRRAGA J.; MEDINA I.; ARBIZA L.; HUERTA-CEPAS J.; GABALDON, T; DOPAZO J.; DOPAZO H.

NUCLEIC ACIDS RESEARCH

OXFORD UNIV PRESS

Año: 2007 vol. 35 p. 38 - 42

0305-1048

Phylemon is an online platform for phylogenetic and evolutionary analyses of molecular sequence data. It has been developed as a web server that integrates a suite of different tools selected among the most popular stand-alone programs in phylogenetic and evolutionary analysis. It has been conceived as a natural response to the increasing demand of data analysis of many experimental scientists wishing to add a molecular evolution and phylogenetics insight into their research. Tools included in Phylemon cover a wide yet selected range of programs: from the most basic for multiple sequence alignment to elaborate statistical meth- ods of phylogenetic reconstruction including meth- ods for evolutionary rates analyses and molecular adaptation. Phylemon has several features that differentiates it from other resources: (i) It offers an integrated environment that enables the direct concatenation of evolutionary analyses, the storage of results and handles required data format conver- sions, (ii) Once an outfile is produced, Phylemon suggests the next possible analyses, thus guiding the user and facilitating the integration of multi-step analyses, and (iii) users can define and save complete pipelines for specific phylogenetic analy- sis to be automatically used on many genes in subsequent sessions or multiple genes in a single session (phylogenomics). The Phylemon web server is available at http://phylemon.bioinfo.cipf.es.