PERSONAL DE APOYO
GARCIA MENENDEZ Sebastian Marcelo Manuel
congresos y reuniones científicas
Título:
ALLOPREGNANOLONE HAS MNEMONIC-ENHANCING EFFECTS IN FEMALE RATS.
Autor/es:
ESCUDERO C; CERION S; S GARCIA; LACONI M; YUNES R; CABRERA R
Lugar:
Rosario, Argentina
Reunión:
Congreso; XLI Reunión Anual de la Sociedad Argentina de Farmacología Experimental (SAFE); 2009
Institución organizadora:
SAFE
Resumen:
Learning and memory processes may be influenced by fluctuations in steroid hormones and neurosteriods, such as Allopregnanolone (Allo). In this study, we investigated the effects of the subcutaneous administration of estrogen (E) and progesterone (P) to ovariectomized (OVX) rats, infused in CA1-CA3 hippocampus regions with Allo (6ìM) or vehicle (30min before training), on the inhibitory avoidance task (Step Down, SD). All groups were trained in SD task and, after 24-h intertrial delay, SD latency was tested. The results were analized vs vehicle by t-test (p
