INVESTIGADORES
MULLER IGAZ Lionel Ivan
congresos y reuniones científicas
Título:
DORSAL MEDIAL PREFRONTAL CORTEX CONTRIBUTES TO CONDITIONED TASTE AVERSION MEMORY CONSOLIDATION AND RETRIEVAL
Autor/es:
VILLAR ME; GONZALEZ MC; IGAZ LM; MEDINA JH; VIOLA H
Lugar:
Buenos Aires
Reunión:
Congreso; XXX Congreso Anual de la Sociedad Argentina de Investigación en Neurociencias (SAN); 2015
Institución organizadora:
Sociedad Argentina de Investigación en Neurociencias (SAN)
Resumen:
The medial prefrontal cortex (mPFC) is known for its role in decision making and memoryprocessing, including the participation in the formation of extinction memories. However,little is known regarding its contribution to aversive memory consolidation. Here wedemonstrate that neural activity and protein synthesis are required in the dorsal mPFC formemory formation of a conditioned taste aversion (CTA) task and that this region isinvolved in the retrieval of recent and remote long-term CTA memory. In addition, bothNMDA receptor and CamKII activity in dorsal mPFC are needed for CTA memoryconsolidation, highlighting the complexity of mPFC functions.
