Eca20 microsatellite polymorphisms in Equine Viral Arteritis infected horses from Argentina

KALEMKERIAN P.B.; METZ G.E.; PERAL GARCIA P.; LOPEZ GAPPA J.; ECHEVERRIA M.G.; GIOVAMBATTISTA G.; DIAZ S.

TISSUE ANTIGENS

WILEY-BLACKWELL PUBLISHING, INC

Año: 2011 p. 1 - 4

0001-2815

We investigated the association of equine arteritis virus (EAV) infection and three short tandem repeat (STR) polymorphisms located within or in close proximity to equine lymphocyte antigen (ELA) region. We used a case–control design as a first approach before proceeding to select candidate genes. One hundred and sixtyfive Silla Argentino horses were taken in 2002 from positive serological detections of EAV in Argentina, to determine whether STR genotypes were correlated to genetic susceptibility to EVA. Allele frequency distribution did not show significant differences between both groups (P = 0.0781). However, in particular alleles, Fisher exact test and odds ratio calculations showed significant values >1 for TKY08 and LEX52, and