INVESTIGADORES
LAMAS Maria Celina
artículos
Título:
Matrices hidrofílicas para la elaboración de comprimidos de liberación controlada con flutamida. Formulación y estudios in vitro
Autor/es:
LAMAS, M. C.; BREGNI, C.; FRIAS, M.
Revista:
BOLLETTINO CHIMICO FARMACEUTICO
Editorial:
Societa Editoriale Farmaceutica
Referencias:
Lugar: Milan; Año: 1998 vol. 137 p. 256 - 260
ISSN:
0006-6648
Resumen:
The features of hydrophilic matrices for the elaboration of sustained released tablets were investigated using flutamide as an active principle. Different formulations were prepared and analyzed. The results indiated that flutamide release in vitro from polymeric matrices correspons to a zero order kinetics.