INVESTIGADORES
PEREZ BRANDAN Cecilia Maria
capítulos de libros
Título:
Vaccine development for Chagas Disease
Autor/es:
ANGEL MARCELO PADILLA; CECILIA PÉREZ BRANDAN; MIGUEL ANGEL BASOMBRIO
Libro:
American Trypanosomiasis
Editorial:
Elsevier
Referencias:
Año: 2010; p. 827 - 848
Resumen:
Vaccines have had an indisputable impact on the control of many important human and veterinary diseases and unquestionably have shaped the health landscape of recent generations. In spite of the crucial benefits obtained with vaccines for diseases like smallpox and poliomyelitis, many tropical diseases, commonly referred to as ?neglected diseases,? suffer from the lack of an effective vaccine. Chagas disease is one of these neglected diseases, and it is a major health problem in Latin American countries, especially the poorest ones. The advantages of a Chagas disease vaccine would be significant not just in terms of public health but also economic and social development. Although some important advances on the comprehension of human immune response to Trypanosoma cruzi infection have occurred, most of our knowledge about immune mechanisms and protective response comes from experimental animal models.Trypanosoma cruzi infection have occurred, most of our knowledge about immune mechanisms and protective response comes from experimental animal models. Trypanosoma cruzi infection have occurred, most of our knowledge about immune mechanisms and protective response comes from experimental animal models. Trypanosoma cruzi infection have occurred, most of our knowledge about immune mechanisms and protective response comes from experimental animal models.