INVESTIGADORES
MARQUEZ Maria Gabriela
artículos
Título:
The effect of testosterone on the immune response. 1_Mechanism of action on antibody forming cells
Autor/es:
SADI UBALDO RIFÉ; MARÍA GABRIELA MÁRQUEZ; ALEJANDRA ESCALANTE; TERESA VELICH.
Revista:
IMMUNOLOGICAL INVESTIGATIONS
Editorial:
New York
Referencias:
Lugar: Marcel Dekker, Inc; Año: 1990 vol. 19 p. 259 - 270
ISSN:
0882-0139
Resumen:
Sex hormones are known to be implicated in humoral and cellular immune responses. In this study we reported the effect of orchidectomy and testosterone replacement on the immune response using T-dependent and T-independent antigens. It was found that the response was dependent on the nature of the antigen employed and on the presence of testosterone. The absence of testosterone receptors in spleen lymphocytes was also found. An hypothesis that testosterone regulates the immune system through the enhancement of suppressive activity is advanced.
