INVESTIGADORES
KNOPOFF Damian Alejandro
congresos y reuniones científicas
Título:
Fighting against resistant bacteria: how long will antibiotics help?
Autor/es:
DAMIAN KNOPOFF
Lugar:
Rio de Janeiro
Reunión:
Congreso; International Congress of Mathematicians ICM; 2018
Resumen:
A mathematical model for bacterial growth, mutations, horizontal transfer and devel-opment of antibiotic resistance is presented. The model is based on the so-called kinetictheory for active particles that is able to capture the main complexity features of the sys-tem. Bacterial and immune cells are viewed as active particles whose microscopic state isdescribed by a scalar variable. Particles interact among them and the temporal evolutionof the system is described by a generalized distribution function over the microscopic state.The model is derived and tested in a couple of case studies in order to confirm its abil-ity to describe one the most fundamental problems of modern medicine, namely bacterialresistance to antibiotics.