Analytical determinations of luteolin

TESIO, ALVARO Y.; ROBLEDO, SEBASTIAN N.

BIOFACTORS

IOS PRESS

Año: 2021

0951-6433

Plants, through the photosynthesis process, produce the substances necessaryfor all the life cycles of nature, which are called "primary metabolites." Moreover,there are some plants that synthesize, in addition to these, other substanceswith more specific functions, which are known as "secondarymetabolites." It is inside this group that flavonoids are located, whose mainfunction is to protect organisms from damage caused by different oxidizingagents. Luteolin (3,4,5,7-tetrahydroxy-flavone) belongs to the sub-class of flavonoidsknown as flavones and is one of 10,000 flavonoids currently known,being one of the most bio-active flavonoids. Its various beneficial properties forhealth, together with the increasing reduction in the use of synthetic antioxidants,make the study of luteolin a very active field. Within this, the quantificationof this molecule has become a subject of very special interest giventhat it is transversal to all fields. In this review article, we aim to give thereader a broad and deep vision of this topic, focusing on the events reported inthe last 5 years and covering all possible techniques related to analytical determinations.We will discuss in terms of advantages and disadvantages betweentechniques, selectivity, sensitivity, costs, time consumption, and reagents aswell as in the complexity of operations.