INVESTIGADORES
HERRERA CANO Natividad Carolina
artículos
Título:
A Review on the Green Synthesis of Benzimidazole Derivatives and Their Pharmacological Activities
Autor/es:
NARDI, MONICA*; HERRERA CANO, NATIVIDAD*; SIMEONOV, S.*; BENCE, RENATA; KURUTOS, A.; SCARPELLI, R.; WUNDERLIN, DANIEL A.; PROCOPIO, ANTONIO
Revista:
Catalysts
Editorial:
MDPI
Referencias:
Año: 2023
ISSN:
2073-4344
Resumen:
Benzimidazoles and their derivatives play an extraordinarily significant role as therapeutic agents, e.g., antiulcer, analgesic, and anthelmintic drugs. The organic synthesis of benzimidazoles and derivatives to obtain active pharmacological compounds represents an important researcharea in organic chemistry. The use of non-environmental organic compounds and application highenergy synthetic methods, the production of waste, and the application of conventional toxic processes are a problem for the pharmaceutical industry and for these important drugs’ synthesis. Thesubstituted benzimidazoles are summarized in this review to provide insight about their organicsynthesis using ecofriendly methods, as well as their pharmacological activities.