Radiofrequency Ablation Using a Novel Insulated-Tip Ablation Catheter Can Create Uniform Lesions Comparable in Size to Conventional Irrigated Ablation Catheters While Using a Fraction of the Energy and Irrigation

A.ARYANA; R. M. IRASTORZA; E. BERJANO; R. J. COHEN; J. KRAUS ; A. HAGHIGHI-MOOD; V. Y. REDDY; A. D'AVILA

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY.

WILEY-BLACKWELL PUBLISHING, INC

Lugar: Londres; Año: 2022

1045-3873

Introduction: During radiofrequency ablation (RFA) using conventional RFA catheters (RFC), ~90% of the energy dissipates into the bloodstream/surrounding tissue. We hypothesized that a novel insulated-tip ablation catheter (SMT) capable of blocking the radiofrequency path, may focus most of the energy into the targeted tissue while utilizing reduced power and irrigation. Methods: This study evaluated the outcomes of RFA using SMT versus an RFC in silico, exvivo and in vivo. Radiofrequency applications were delivered over porcine myocardium (ex vivo) and porcine thigh F muscle preparations superfused with heparinized blood (in vivo). Altogether, 274 radiofrequency applications were delivered using SMT (4?15 W, 2 or 20 mL/min) and 74 applications using RFC (30 W, 30 mL/min).Results: RFA using SMT proved capable e of directing 66.8% of the radiofrequency energy into the targeted tissue. Accordingly, low power?low r irrigation RFA using SMT (8?12 W, 2 mL/min) yielded lesion sizes comparable to RFC, whereas high power?high irrigation (15 W, 20 mL/min) RFA with SMT yielded lesions larger than RFC (P