Síntesis de nanoensambles de nevirapina con diacrilato de polietilenglicol

COSTAS DOS SANTOS E.; GLISONI R.J.; FABIAN L.; SOSNIK A.; MOGLIONI A.G.

Mar del Plata, Argentina

Simposio; XIX Simposio Nacional de Química Orgánica; 2013

Sociedad Argentina de Investigación en Química Orgánica

The design of nano-molecular transporters such as "hydrogels", based on PEG and chemically modified active compounds, significantly improves their hidrosolubilization.1 Considering that nevirapine (NVP) has proven highly effective in the highly active antiretroviral therapy (HAART), when used as first choice for the treatment of antiretroviral-naive patients, but has low aqueous solubility, investigation about its improvement is necessary.