Shock detection in dynamics of single-headed motor proteins KIF1A via Jensen-Shannon divergence

J. SPARACINO; P.W. LAMBERTI; C.M.ARIZMENDI

PHYSICAL REVIEW E

AMER PHYSICAL SOC

Año: 2011 vol. 84 p. 419071 - 419078

1539-3755

Information theoretic quantities are useful tools to characterize symbolic sequences. In this paper, we use theJensen-Shannon divergence to study symbolic binary sequences that represent the stationary state of a lattice-gasmodel describing the traffic of monomeric kinesin KIF1A. More specifically, the constructed binary sequencesrepresent the state of a microtubule protofilament at different adenosine triphosphate (ATP) and KIF1A motorconcentrations in the cytosol. The model presents some stationary regimes with phase coexistence. By using theJensen-Shannon divergence, we develop a method of analysis that allows us to identify cases in which phasecoexistence occurs and, for these cases, to locate the position of the interphase that separates the regions withdifferent phase.