INVESTIGADORES
GIRAUD BILLOUD Maximiliano German
artículos
Título:
Uric acid deposits and estivation in the invasive apple-snail, Pomacea canaliculata
Autor/es:
GIRAUD BILLOUD, MAXIMILIANO.; ABUD, MARÍA A.; CUETO, JUAN A.; VEGA, ISRAEL A.; CASTRO-VAZQUEZ, ALFREDO.
Revista:
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY
Editorial:
ELSEVIER SCIENCE INC
Referencias:
Año: 2011 vol. 158 p. 506 - 512
ISSN:
1095-6433
Resumen:
The physiological ability to estivate is relevant for the maintenance of population size in the invasive Pomacea
canaliculata. However, tissue reoxygenation during arousal from estivation poses the problem of acute
oxidative stress. Uric acid is a potent antioxidant in several systems and it is stored in specialized tissues of P.
canaliculata. Changes in tissue concentration of thiobarbituric acid reactive substances (TBARS), uric acid and
allantoin were measured during estivation and arousal in P. canaliculata. Both TBARS and uric acid increased
two-fold during 45 days estivation, probably as a consequence of concomitant oxyradical production during
uric acid synthesis by xanthine oxidase. However, after arousal was induced, uric acid and TBARS dropped to
or near baseline levels within 20 min and remained low up to 24 h after arousal induction, while the urate
oxidation product allantoin continuously rose to a maximum at 24 h after induction, indicating the
participation of uric acid as an antioxidant during reoxygenation. Neither uric acid nor allantoin was detected
in the excreta during this 24 h period. Urate oxidase activity was also found in organs of active snails, but
activity shut down during estivation and only a partial and sustained recovery was observed in the midgut
gland.Pomacea
canaliculata. However, tissue reoxygenation during arousal from estivation poses the problem of acute
oxidative stress. Uric acid is a potent antioxidant in several systems and it is stored in specialized tissues of P.
canaliculata. Changes in tissue concentration of thiobarbituric acid reactive substances (TBARS), uric acid and
allantoin were measured during estivation and arousal in P. canaliculata. Both TBARS and uric acid increased
two-fold during 45 days estivation, probably as a consequence of concomitant oxyradical production during
uric acid synthesis by xanthine oxidase. However, after arousal was induced, uric acid and TBARS dropped to
or near baseline levels within 20 min and remained low up to 24 h after arousal induction, while the urate
oxidation product allantoin continuously rose to a maximum at 24 h after induction, indicating the
participation of uric acid as an antioxidant during reoxygenation. Neither uric acid nor allantoin was detected
in the excreta during this 24 h period. Urate oxidase activity was also found in organs of active snails, but
activity shut down during estivation and only a partial and sustained recovery was observed in the midgut
gland.. However, tissue reoxygenation during arousal from estivation poses the problem of acute
oxidative stress. Uric acid is a potent antioxidant in several systems and it is stored in specialized tissues of P.
canaliculata. Changes in tissue concentration of thiobarbituric acid reactive substances (TBARS), uric acid and
allantoin were measured during estivation and arousal in P. canaliculata. Both TBARS and uric acid increased
two-fold during 45 days estivation, probably as a consequence of concomitant oxyradical production during
uric acid synthesis by xanthine oxidase. However, after arousal was induced, uric acid and TBARS dropped to
or near baseline levels within 20 min and remained low up to 24 h after arousal induction, while the urate
oxidation product allantoin continuously rose to a maximum at 24 h after induction, indicating the
participation of uric acid as an antioxidant during reoxygenation. Neither uric acid nor allantoin was detected
in the excreta during this 24 h period. Urate oxidase activity was also found in organs of active snails, but
activity shut down during estivation and only a partial and sustained recovery was observed in the midgut
gland.P.
canaliculata. Changes in tissue concentration of thiobarbituric acid reactive substances (TBARS), uric acid and
allantoin were measured during estivation and arousal in P. canaliculata. Both TBARS and uric acid increased
two-fold during 45 days estivation, probably as a consequence of concomitant oxyradical production during
uric acid synthesis by xanthine oxidase. However, after arousal was induced, uric acid and TBARS dropped to
or near baseline levels within 20 min and remained low up to 24 h after arousal induction, while the urate
oxidation product allantoin continuously rose to a maximum at 24 h after induction, indicating the
participation of uric acid as an antioxidant during reoxygenation. Neither uric acid nor allantoin was detected
in the excreta during this 24 h period. Urate oxidase activity was also found in organs of active snails, but
activity shut down during estivation and only a partial and sustained recovery was observed in the midgut
gland.. Changes in tissue concentration of thiobarbituric acid reactive substances (TBARS), uric acid and
allantoin were measured during estivation and arousal in P. canaliculata. Both TBARS and uric acid increased
two-fold during 45 days estivation, probably as a consequence of concomitant oxyradical production during
uric acid synthesis by xanthine oxidase. However, after arousal was induced, uric acid and TBARS dropped to
or near baseline levels within 20 min and remained low up to 24 h after arousal induction, while the urate
oxidation product allantoin continuously rose to a maximum at 24 h after induction, indicating the
participation of uric acid as an antioxidant during reoxygenation. Neither uric acid nor allantoin was detected
in the excreta during this 24 h period. Urate oxidase activity was also found in organs of active snails, but
activity shut down during estivation and only a partial and sustained recovery was observed in the midgut
gland.P. canaliculata. Both TBARS and uric acid increased
two-fold during 45 days estivation, probably as a consequence of concomitant oxyradical production during
uric acid synthesis by xanthine oxidase. However, after arousal was induced, uric acid and TBARS dropped to
or near baseline levels within 20 min and remained low up to 24 h after arousal induction, while the urate
oxidation product allantoin continuously rose to a maximum at 24 h after induction, indicating the
participation of uric acid as an antioxidant during reoxygenation. Neither uric acid nor allantoin was detected
in the excreta during this 24 h period. Urate oxidase activity was also found in organs of active snails, but
activity shut down during estivation and only a partial and sustained recovery was observed in the midgut
gland.