INVESTIGADORES
EIRIN Maria Emilia
artículos
Título:
Decreasing trends in HTLV-1/2 but stable HIV-1 infection among replacement donors in Argentina
Autor/es:
CAROLINA BERINI; SILVINA GENDLER; M. SUSANA PASCUCCIO; MARIA EMILIA EIRIN; WILLI MCFARLAND; KIMBERLY PAGE; LUISA CARNEVALI; EDWARD MURPHY; MIRNA BIGLIONE
Revista:
JOURNAL OF MEDICAL VIROLOGY
Editorial:
WILEY-LISS, DIV JOHN WILEY & SONS INC
Referencias:
Lugar: Hoboken; Año: 2010 vol. 82 p. 873 - 877
ISSN:
0146-6615
Resumen:
In Argentina, current procedures to ensure safety
of the blood supply for transfusion include
reviewing the records of blood donors with
particular attention to the serologic detection of
specific blood borne infections. Data of 28,483
blood donations received from January 1, 2003 to
December 31, 2008 in a public hospital in Buenos
Aires were analyzed. Of the 28,483 blood donations,
7,442 (26.1%) were female donors, 14,582
(51.2%) were younger than 35 years old, and
23,746 (83.4%) were Argentine. Among all, only
285 (1.0%) were voluntary donations. The prevalence
of HTLV-1/2 was 0.1% (95% CI 0.0630.15),
being 0.07% for HTLV-1 and 0.03% for HTLV-2.
The prevalence of HIV-1 was 0.2% (95% CI 0.110
0.206). No HIV-1/HTLV-1/2 co-infections were
detected among volunteer donors. During this
study period, data confirm that HTLV-1/2 infection
was not endemic in Buenos Aires, and that
the prevalence of HTLV-1/2 decreased throughout
while HIV-1 was stable. Due to the small
number of voluntary donations, we could not
conduct comparisons to infection rates in
replacement donations. Although there have
been several ongoing programs aimed at recruiting
voluntary blood donations and changing
from mostly replacement donations to an altruistic
system of blood donations, Argentina is still
far from reaching this objective. Additional
efforts are needed in order to increase and
assure the quality of blood supply in this country.