Quinolines: Microwave-assisted synthesis and their antifungal, anticancer and radical scavenger properties

LIBERTO, N.; SIMÕES, J.; DE PAIVA SILVA, S.; DA SILVA, C.; MODOLO, L.; DE FÁTIMA, A.; SILVA, L.; DERITA, M.; ZACCHINO, S.; PORTILLA ZUÑIGA, O.; ROMANELLI, G.; FERNANDES, S.

BIOORGANIC & MEDICINAL CHEMISTRY.

PERGAMON-ELSEVIER SCIENCE LTD

Lugar: Amsterdam; Año: 2017 vol. 25 p. 1153 - 1162

0968-0896

An efficient method for the synthesis of quinolines using microwave irradiation was developed providing 28 quinolines with good yields. The reaction procedures are environmentally friendly, convenient, mild and of easy work-up. Quinolines were evaluated for their antifungal, anticancer and antioxidant propertiesand exhibited high activities in all tests performed.