INVESTIGADORES
DERITA Marcos Gabriel
artículos
Título:
Synthesis and Evaluation of Novel E-2-(2-Thienyl)- and Z-2-(3-Thienyl)-3-Arylacrylonitriles as Antifungal and Anticancer Agents
Autor/es:
QUIROGA, J.; COBO, D.; INSUASTY, B.; ABONÍA, R.; NOGUERAS, M.; COBO, J.; VÁSQUEZ, Y.; GUPTA, M.; DERITA, M.; ZACCHINO, S.
Revista:
ARCHIV DER PHARMAZIE.
Editorial:
Wiley Interscience
Referencias:
Lugar: Berlín, Alemania; Año: 2007 vol. 340 p. 603 - 606
ISSN:
0365-6233
Resumen:
A series of 3-aryl-2-(2-thienyl)acrylonitriles 7 and 3-aryl-2-(3-thienyl)acrylonitriles 8 where synthesized by the reaction of aromatic aldehydes 6 with 2- and 3-thienylacetonitriles 4 and 5, and evaluated for antifungal and cytotoxic activities against a panel of opportunistic and pathogenic fungi and three different cancer cell lines, respectively.
