A dynamically coherent pattern of rhythms that matches between distant species across the evolutionary scale

JACKELYN KEMBRO; ANA GEORGINA FLESIA; PAULA SOFIA NIETO; JORGE MARTIN CALIVA; DAVID LLOYD; SONIA CORTASSA; MIGUEL A. AON

Scientific reports

Nature Publishing Group

Lugar: New York; Año: 2023 vol. 13 p. 1 - 16

2045-2322

We address the temporal organization of circadian and ultradian rhythms, crucial for understandingbiological timekeeping in behavior, physiology, metabolism, and alignment with geophysical time.Using a newly developed fve-steps wavelet-based approach to analyze high-resolution time seriesof metabolism in yeast cultures and spontaneous movement, metabolism, and feeding behaviorin mice, rats, and quails, we describe a dynamically coherent pattern of rhythms spanning over abroad range of temporal scales (hours to minutes). The dynamic pattern found shares key featuresamong the four, evolutionary distant, species analyzed. Specifcally, a branching appearance givenby splitting periods from 24 h into 12 h, 8 h and below in mammalian and avian species, or from 14 hdown to 0.07 h in yeast. Scale-free fuctuations with long-range correlations prevail below~ 4 h.Synthetic time series modeling support a scenario of coexisting behavioral rhythms, with circadianand ultradian rhythms at the center of the emergent pattern observed.