INVESTIGADORES
ROMORINI Leonardo
artículos
Título:
Generation of a human induced pluripotent stem cell line from a familial Alzheimer's disease PSEN1 T119I patient
Autor/es:
ISAJA, LUCIANA; SOLEDAD RODRÍGUEZ-VARELA, MARÍA; MARAZITA, MARIELA; MUCCI, SOFÍA; ITZCOVICH, TATIANA; CHREM-MÉNDEZ, PATRICIO; NIIKADO, MATÍAS; LUJÁN FERRIOL-LAFFOUILLERE, SOFÍA; ALLEGRI, RICARDO; MARTINETTO, HORACIO; EMILIO SEVLEVER, GUSTAVO; ELIDA SCASSA, MARÍA; IGNACIO SURACE, EZEQUIEL; ROMORINI, LEONARDO
Revista:
STEM CELL RESEARCH
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Año: 2021
ISSN:
1873-5061
Resumen:
Human induced pluripotent stem cells (hiPSC) line FLENIi001-A was reprogrammed from dermal fibroblasts using the lentiviral-hSTEMCCA-loxP vector. Fibroblasts were obtained from a skin biopsy of a 72- year-old Caucasian male familial Alzheimer's disease patient carrying the T119I mutation in the PSEN1 gene. PSEN1 genotype was maintained and stemness and pluripotency confirmed in the FLENIi001-A hiPSC line.
