Lens as a novel target of urban air pollutants: evaluation of the redox balance.

LASAGNI VITAR, ROMINA M.; HVOZDA ARANA, AILEN G.; MARCHINI, TIMOTEO; TAU, JULIA; MARTINEFSKI, MANUELA; REIDES, CLAUDIA; TRIPODI, VALERIA; LLESUY, SUSANA; BERRA, ALEJANDRO; EVELSON, PABLO; FERREIRA, SANDRA

Maryland

Congreso; 2020 ARVO Meeting; 2020

ARVO

Purpose : Particulate matter (PM) present in air pollution induces adverse e􀃠ects on the eye. Oxidative stress has been suggested to play a key role in the ocular surface response triggered by urban air pollutants. It is well-known that lens antioxidant system maintains the redox status of nearby ocular structures. The aim of the study was to evaluate the redox balance in mice lens after the exposure to urban air pollution.Methods : 8-week-old Balb/c male mice were exposed to urban air or (r=-0.9114, p