Oxygen Metabolism in the Cardiorespiratory System After an Acute Exposure to Ni-doped Nanoparticules

MAGNANI, NATALIA; MARCHINI, TIMOTEO; VANASCO, VIRGINIA; GARCÉS, MARIANA; MEBERT, ANDREA; DESIMONE, MARTIN; DIAZ, LUIS; ALVAREZ, SILVIA; EVELSON, PABLO

Chascomus

Congreso; IV Latin American Meeting on Biological Inorganic Chemistry; 2014

LABIC2014

The use of metal coated NP was a useful approach to evaluate the effect of the metal ions present in air particles, since they are exposed in a similar way than PM. The Ni relative contribution in cardiopulmonary O2 metabolism alterations appears to be an important area of study in inflammatory conditions, triggered by PM. These findings contribute to the understanding of the cardiopulmonary O2 metabolism alterations, where oxidative stress and inflammation may play a predominant role, in association with transition metals present in environmental PM.