INVESTIGADORES
CHIMENO ZOTH Silvina Andrea
artículos
Título:
Recombinant vaccines and infectious bursal disease virus
Autor/es:
LUCERO MARIA SOLEDAD; EVANGELINA GOMEZ; CARBALLEDA JUAN MANUEL; GRAVISACO MARIA JOSE; CHIMENO ZOTH SILVINA; BERINSTEIN ANALIA
Revista:
CAB Reviews
Editorial:
CABI
Referencias:
Año: 2012 vol. 7 p. 1 - 11
ISSN:
1749-8848
Resumen:
Infectious bursal disease virus (IBDV) is the aetiological agent of infectious bursal disease (IBD), animmunosuppressive and highly contagious disease that affects young birds causing importanteconomic losses in the poultry industry worldwide. Currently, vaccination programmes withinactivated and live-attenuated viruses have been used to prevent IBD. However, these vaccinespresent a number of disadvantages, mainly because of their viral nature. Consequently, in the lasttwo decades, many studies have been conducted in order to replace conventional virus-basedvaccines by new, rationally designed vaccines that are safer as well as effective. In this review, wewill present a background on the disease and its causative agent, and focus on the development ofnew generation vaccines against this significant poultry disease.