INVESTIGADORES
RADIVOY Gabriel Eduardo
artículos
Título:
Reduction of carbonyl compounds and imines using the CuCl2.2H20-Li-DTBB (cat.)combination
Autor/es:
F. ALONSO; C. VITALE; G. RADIVOY; M. YUS
Revista:
SYNTHESIS-STUTTGART
Editorial:
Georg Thieme
Referencias:
Lugar: Stuttgart - Alemania; Año: 2003 p. 443 - 447
ISSN:
0039-7881
Resumen:
The reaction of different carbonyl compounds and imines with a mixture of copper(II) chloride dihydrate, an excess of lithium sand, and a catalytic amount of 4,4-di-tert-butylbiphenyl (DTBB, 5 mol%) in THF at room temperature, led to the formation of the corresponding alcohols and amines, respectively. The process was also applied to the transformation of a,b-unsaturated carbonyl compounds into the corresponding saturated alcohols. The use of the deuterated copper salt CuCl2·2D2O allowed the preparation of the corresponding deuterated products.
