First clinical trials in Latin America: the ARG algorithm without CHO counting.

RICARDO SANCHEZ PEÑA; PATRICIO COLMEGNA; FABRICIO GARELLI; HERNÁN DE BATTISTA; GROSEMBACHER, LUIS; CHERÑAVVSKY, DANIEL; CAMPOS-NÁÑEZ, ENRIQUE; BRETON, MARC

Viena

Conferencia; 11th International Conference on Advanced Technologies & Treatments for Diabetes; 2018

Kenes

Background and AimsThis trial evaluated an Artificial Pancreas with the new Automatic Regulation of Glucose (ARG) algorithm for the first time in Latin America. The algorithm was designed by a research team in Argentina from ITBA, UNQ, and UNLP.MethodFive subjects with T1DM participated in this study. Each patient wore a DEXCOM G4 CGM and a Roche Accu-Check Combo CSII during an open-loop (OL) period at home, and the same hardware connected to a Diabetes Assistant (DiAs) cellphone at Hospital. In this last case, the ARG algorithm was loaded in the DiAs cellphone to perform the closed-loop (CL) test. For comparison, both periods had a duration of 36hrs. The OL procedure was performed with the usual basal-bolus method. The CL procedure did not require CHO counting for any of the five meals.ResultsFor the total 36hr period, the CL results were: average glycaemia 88.6% in [70-250]mg/dl; 74.7% in [70-180]mg/dl; 5.8%