INVESTIGADORES
CONDE Cecilia Beatriz
artículos
Título:
Microtubule assembly, organization and dynamics in axons and dendrites
Autor/es:
CONDE, CECILIA; CÁCERES, ALFREDO
Revista:
Nature Reviews Neuroscience
Editorial:
Nature Publishing Group
Referencias:
Año: 2009 vol. 10 p. 319 - 332
ISSN:
1471-003X
Resumen:
During the past decade enormous advances have been made in our understanding of the basic molecular machinery that is involved in the development of neuronal polarity. Far from being mere structural elements, microtubules are emerging as key determinants of neuronal polarity. Here we review the current understanding of the regulation of microtubule assembly, organization and dynamics in axons and dendrites. These studies provide new insight into microtubules´ function in neuronal development and their potential contribution to plasticity. © 2009 Macmillan Publishers Limited.