Chitosan can improve antimicrobial treatment independently of bacterial lifestyle, biofilm biomass intensity and antibiotic resistance pattern in non-aureus staphylococci (NAS) isolated from bovine clinical mastitis

BRESER ML; TISERA L; ORELLANO MS; BOHL LP; ISAAC P; BIANCO ID; PORPORATTO C

Antimicrobial resistance: Agriculture, environment and public health within one health framework

Frontiers

Lugar: Lausanne; Año: 2023; p. 1 - 191

Antimicrobial resistance (AMR) has attracted increasing attention from governments and researchers in recent years, as it is considered one of the major public health challenges of this century. Infections caused by antimicrobial-resistant bacteria are more severe and respond less well to treatment than those caused by susceptible bacteria. The main factors contributing to this health crisis are the overuse/misuse of antibiotics in humans and animals and the spread of resistant bacteria and resistance determinants within and between these sectors and globally. In this context, AMR is seen as "a health theme," both as a cause and a solution, covering the interactions between animals, the environment, and humans.Over the years, the extensive literature approach to AMR has focused on food animals, public health, and wildlife health. However, many studies have demonstrated that antimicrobial resistance is an ecological problem, as most bacteria and their genes move relatively quickly between animals, the environment, and humans. Given the critical and interdependent nature of antimicrobial resistance in animals, the environment, and public health, it is logical to take a ´one health´ approach in addressing this issue. At the same time, the past decade has seen a growing interest in the issue of AMR on a global scale, an interest that stems from the growing concern among the scientific community and governments. As a result, a growing number of proposals and policies have emerged. However, the existing literature does not have a systematic conceptualization, and a direct comparison of policy processes requires an understanding of each participant´s perspectives, values, interests, and goals. It is important to understand both the scientific perspective and the actions advocated by global health actors.Therefore, this Research Topic addresses resistance by collecting the work of doctors, veterinarians, environmental scientists, public health professionals, wildlife experts, and many others on antimicrobial resistance within the One Health framework and from a global perspective. We encourage submissions related to, but not limited to, the following• The impact of AMR on human and/or animal health• Innovative technologies and strategies to combat AMR• AMR as a development issue in low- and middle-income countries• AMR is a threat to the stability of health systems, especially in times of crisis.