INVESTIGADORES
CANCELA Liliana Marina
artículos
Título:
Chronic Restraint Attenuates the Immunosuppressive Response Induced by Novel Aversive Stimuli
Autor/es:
ANA MARL~ BASSO, *12 MIRTA DEPIANTE-DEPAOLI,T LILIANA CANCELA .2 AND VICTOR A. MOLINA*
Revista:
PHYSIOLOGY AND BEHAVIOR
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Año: 1994 vol. 55 p. 1151 - 1155
ISSN:
0031-9384
Resumen:
BASSO, A. M., M. DEPIANTE-DEPAOLI, L. CANCELA AND V. A. MOLINA. Chronic restraint attenuates the immunosuppressive
response induced by novel aversive stimuli. PHYSIOL BEHAV 55(6) 1151-1155, 1994.--The exposure to a novel
aversive event, such as foot shock, induced a decrease in the percentage of T lymphocytes and a clear reduction in the delayedtype
hypersensitivity reaction (DTH). This immunosuppressive response to an acute stressor was absent in rats that were previously
exposed to a chronic immobilization stress regime (2 h daily during 7 consecutive days), but was still present in animals with
prior exposure to only one or three restraint sessions. No stress effect was observed in other immunologic parameters, such as the
percentage of B lymphocytes or the hemagglutinin titer, in any of the experimental treatments. The possible involvement of central
adaptive mechanisms in the attenuation of the immunosuppressive response induced by an acute stress is discussed.