INVESTIGADORES
CABRERA KREIKER Ricardo Jorge
artículos
Título:
Periodic maternal deprivation and lesion of anterodorsal thalami nuclei induce alteration on hypophyso adrenal system activity in adult rats
Autor/es:
MARTA M. SUÁREZ; MARÍA A. RIVAROLA; SANDRA M. MOLINA; NORMA I. PERASSI; GLORIA M. LEVIN; RICARDO CABRERA
Revista:
LIFE SCIENCES
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2001 vol. 69 p. 803 - 813
ISSN:
0024-3205
Resumen:
AbstractThe hypothalamic-pituitary-adrenal (HPA) axis is normally regulated by extrahypothalamic limbicstructures, among these, the anterodorsal thalami nuclei (ADTN), which exert an inhibitory influenceon HPA, in basal and acute stress conditions in rats. In the present work we have investigated whether neonatal maternal deprivation (MD) produces long-term changes in the ADTN regulation of HPA activity. Maternal deprivation, in female rats, for 4,5 hs daily, during the first 3 weeks of life, produced at 3 months old, a significant decrease in plasma ACTH concentration (p
