WORKING MEMORY AND EXECUTIVE FUNCTIONS DISPLAYED IN DIFFERENT STRAINS OF RATS IN THE HOLE BOARD TEST

ORCE, I. G.; CALDERÓN, M.; SERRANO, L.; SORIA, G.; FRAILE, M.; LANDA, A. I.; GARGIULO, P. A.

Potrero de los Funes, San Luis, Argentina.

Simposio; XXIV Reunión Científica Anual de la Sociedad de Biología y IV reunión científica de microscopía.; 2006

Hole board test is usually accepted as a working memory and executive functions test. In the genetic of behaviour comparisons between individual patterns despite environmental conditions are studied. The aim of the present study is to evaluate working memory and executive functions comparing behavioural patterns displayed by four different strains of Rattus norvegicus (Holtzman [H], Wistar [W], Atriche IPL [A] y Sprague Dawley [SD]). Male rats weighing 230-250 g (n=15) were used. The following parameters were considered: ambulatory movements, non ambulatory movements, number of movements, rearing, horizontal activity, number of fecal boli, sniffing, head dipping and total exploration. The A strain showed a significant increase of ambulatory movements when compared with H (p