PHANTOM GELS TOWARDS MEDICINE IMPROVEMENT: USES FOR MAGNETIC DEVICE TESTS AND ENHANCEMENTS ON MAGNETIC-DEPENDENT CLINICAL TECHNIQUES

LAURA M. SANCHEZ; MAGDA LORENA ARCINIEGAS; VERA A. ALVAREZ; JIMENA S. GONZALEZ

Materials for Biomedical Engineering: Nanomaterials-Based Drug Delivery

Elsevier

Año: 2019; p. 435 - 456

A phantom is an especially designed material that should respond similarly to the desired humanorgan/tissue. Biomedical phantoms have a broad set of applications, from uses for magneticdevices tests and enhancements on magnetic-dependent clinical techniques, to medical studentstraining and complex surgery planning.Among magnetic devices that could be tested are embolic particles, materials useful forhyperthermia treatments and others employed in magnetofection therapy. These magnetictherapies are considered potential key solutions in malignant tumor and cancer treatments due totheir relative simple implementation and reduced secondary undesired effects. In this sense, thepossibility to test novel magnetic devices on phantoms simulating real human organ/tissue opensup a huge path of possibilities.Magnetic resonance imaging, commonly known as MRI, is a useful diagnostic tool broadlyapplied for clinical diagnostic and scientific research. Phantoms could be used to study how toenhance MRI quality, reducing signal noise.Selecting the appropriate materials and techniques in order to ensure correct reproduction of thespecific property or group of properties, such as morphological, mechanical, electric and/orelectromagnetic, is real challenge..  The soft tissue ? simulating materials have a widely importance because are the previous stepto the magnetic therapy. All the laboratory and dosage assays can be made in a phantom. Manypolymeric gels are suggested as convenient materials for simulating the thermal, mechanical andpermeability behavior of biological tissues in experimental studies of heat deposition byelectromagnetic means or by introducing a ferrofluid (by means a magnetofection therapy).