INVESTIGADORES
CZIBENER Cecilia
congresos y reuniones científicas
Título:
CONTROL OF THE O-ANTIGEN CHAIN LENGTH IN Brucella
Autor/es:
ROMANI A; DEL GIUDICE MG; CASABUONO AC; COUTO AS; CZIBENER C; UGALDE JE
Lugar:
Buenos Aires
Reunión:
Congreso; Reunion Conjunta de Sociedades de Biociencias de Argentina; 2017
Institución organizadora:
Comite organizador de Reunión Conjunta de sociedades de Biociencias
Resumen:
Previous results from our group indicated that Brucella actively controls the length of the O-antigen and in the search for putative genes that could play a role in this control we identified wbkB, a gene with no known function and present in the O-antigen synthesis cluster that codes for a protein with a putative glycosiltransferase domain. A deletion mutant in wbkB produced longer O-antigen chains and showed a reduced virulence in intracellular replication assays.
