INVESTIGADORES
RAJAL Veronica Beatriz
artículos
Título:
Analysis of the circulation of hepatitis A virus in Argentina since vaccine introduction
Autor/es:
MARÍA D. BLANCO FERNÁNDEZ; C. TORRES; GABRIELA RIVIELLO-LÓPEZ; HUGO R. POMA; VERÓNICA B. RAJAL; SILVIA NATES; DANIEL CISTERNA; RODOLFO H. CAMPOS; VIVIANA A. MBAYED
Revista:
JOURNAL OF CLINICAL VIROLOGY : THE OFFICIAL PUBLICATION OF THE PAN AMERICAN SOCIETY FOR CLINICAL VIROLOGY.
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2012 vol. 18 p. 548 - 551
ISSN:
1386-6532
Resumen:
Hepatitis A virus (HAV) has shown intermediate endemicity in
Argentina, but its incidence has decreased since vaccine introduction
in 2005. Environmental surveillance was conducted in
five rivers from Argentina from 2005 to 2012, complementing
clinical information. HAV detection decreased since 2005,
although its circulation continues, maintaining viral diversity but
not undergoing antigenic drift. Most sequences belonged to subgenotype
IA, closely related to Argentinean clinical sequences,
but one belonged to proposed subgenotype IC, previously undetected
in the country. Environmental surveillance might contribute
to monitoring the single-dose vaccination schedule,
representing not only strains causing disease but also the circulating
population and the viral introductions.