INVESTIGADORES
LEBLANC Jean Guy Joseph
artículos
Título:
Lactobacillus fermentum CRL 722 is able to deliver active alpha-Galactosidase activity in the small intestine of rats
Autor/es:
LEBLANC, J.G.; PIARD, J.-C.; SESMA, F.; SAVOY DE GIORI, G.
Revista:
FEMS MICROBIOLOGY LETTERS
Editorial:
Blackwell Publishing
Referencias:
Lugar: Malden, MA, EE.UU.; Año: 2005 vol. 248 p. 177 - 182
ISSN:
0378-1097
Resumen:
Alpha-galactooligosaccharides (alpha-GOS) found in legumes such as soybeans can cause gastrointestinal disorders since mammals lack alpha-galactosidase (alpha-Gal) in the small intestine which is necessary for their hydrolysis. Lactobacillus fermentum CRL 722 is a lactic acid bacterium (LAB) capable of degrading alpha-GOS due to its elevated alpha-Gal activity. When conventional rats were fed live L. fermentum CRL 722 or cell-free extracts of this strain, a short-lived alpha-Gal activity was detected in the upper gastrointestinal tract. The safety of this LAB was also assessed. L. fermentum CRL 722 could thus be used as a vehicle to safely confer alpha-Gal in the small intestine of monogastric animal.
