Increased angiogenesis elicited by boron-containing bioactive glass.

HARO DURAND L; VARGAS G; GONGORA A; GOMEZ M; CADENA V; ROMERO M,; VERA MESONES R; PORTO LÓPEZ JM; BOCCACCINI AR; ZAGO MP; BALDI A; GORUSTOVICH A

Congreso; World Conference on Regenerative Medicine.; 2011

Background Increasing evidence in the literature shows that the use of bioactive glasses (BGs) in biomaterial-based tissue-engineering strategies may improve vascularization and wound healing stimulating the neoformation of blood vessels in response to the release of soluble ions. Objective The objective of this study was to evaluate the in vitro and in vivo angiogenic potential of borosilicate BG ionic dissolution products (IDPs). Materials & methods The extracts containing the IDPs of BGs were prepared by soaking 1% w/v 45S5 BG particles (