INVESTIGADORES
ORTEGA Maria Gabriela
artículos
Título:
Prenylated Flavanones with Anti-tyrosinase Activity from Dalea boliviana
Autor/es:
MARIANA PERALTA; MARIA GABRIELA ORTEGA; ALICIA MARIEL AGNESE.; JOSÉ CABRERA,
Revista:
JOURNAL OF NATURAL PRODUCTS
Editorial:
AMER CHEMICAL SOC
Referencias:
Año: 2011 vol. 74 p. 158 - 162
ISSN:
0163-3864
Resumen:
Three new prenylated flavanones, (2S)-5,7,2´´-trihydroxy-5´-(1´´´,1´´-dimethylallyl)-8-prenylflavanone (1),(2S)-5,7,2´-trihydroxy-8,30-diprenylflavanone (2), and (2S)-5,2´-dihydroxy-6´´,6´´-dimethylchromeno-(7,8:200,300)-30-prenylflavanone (3), and a known chromeno (dimethylpyrano) flavanone, obovatin (4), were isolated from the n-hexane extract of Dalea boliviana roots. The compounds were evaluated in vitro in relation to their inhibitory effect on the tyrosinase activity by using a spectrophotometric method