Bioactivities of Chuquiraga straminea Sandwith, subfamily barnadesioideae

MENDIONDO ME; JUAREZ B; ZAMPINI I. C.; ISLA M. I.; ORDOñEZ R. M.

NATURAL PRODUCT COMMUNICATIONS

NATURAL PRODUCTS INC

Lugar: Westerville, Ohio; Año: 2011 vol. 6 p. 965 - 968

1934-578X

Methanolic extracts of Chuquiraga straminea Sandwith, subfamily Barnadesioideae (Asteraceae) showed the presence of quercetin-3-Oglucoside, quercetin-3-O-rutinoside, kaempferol,  kaempferol-3-O-glucoside and kaempferol-3-O-rutinoside. Antioxidant and antimicrobialactivity was determined. The total extracts showed antioxidant activity by DPPH and ABTS method (SC50 14.5 to 34.9 ìg/mL). A significantly positive correlation was observed between the antioxidant activity and the total phenolics (R2>0.93). The extracts were active against ten methicillin resistant and sensitive Staphylococcus aureus strains isolated from nosocomial infection (MIC values between 200 to 800 ìg/mL). These preliminary studies are highly interesting as they open new ways for further applications in the treatment of infections by methicillin resistant S. aureus.