INVESTIGADORES
BRACCA Andrea Beatriz Juana
artículos
Título:
Relevant Developments in the Use of Three‐Component Reactions for the Total Synthesis of Natural Products. The last 15 Years
Autor/es:
LARGHI, ENRIQUE L.; BRACCA, ANDREA B. J.; SIMONETTI, SEBASTIAN O.; KAUFMAN, TEODORO S.
Revista:
ChemistryOpen
Editorial:
Wiley
Referencias:
Año: 2024
ISSN:
2191-1363
Resumen:
Multicomponent reactions (MCRs) offer a highly useful and valuable strategy that can fulfill an important role in synthesizing complex polysubstituted compounds, by simplifying otherwiselong sequences and increasing their efficiency. The total synthesis of selected natural products employing three-component reactions as their common strategic MCR approach, is reviewed on a case-by-case basis with selected targets conquered during the last 15 years. The revision includesdetailed descriptions of the selected successful sequences; relevant information on the isolation, and bioactivity of the different natural targets is also briefly provided.
