Galectin-8 in the onset of the immune response and inflammation

TRIBULATTI MARÍA VIRGINIA; CARABELLI, JULIETA; PRATO, CECILIA ARAHÍ; CAMPETELLA, OSCAR

GLYCOBIOLOGY

OXFORD UNIV PRESS INC

Lugar: Oxford; Año: 2020 vol. 30 p. 134 - 142

0959-6658

Galectins (Gals), a family of mammalian lectins, have emerged as key regulators of the immune response, being implicated in several physiologic and pathologic conditions. Lately, there is increasing data regarding the participation of Galectin-8 (Gal-8) in both the adaptive and innate immune responses, as well as its high expression in inflammatory disorders. Here we focus on the pro- and anti-inflammatory properties of Gal-8, and discuss the potential use of this lectin in order to shape the immune response, according to the context.