INVESTIGADORES
DELPICCOLO Carina Maria Lujan
artículos
Título:
Formation of Dihydrouracils via Cyclization of N-substituted-3-thioureidopropanoic acids and Facile Desulfurization
Autor/es:
DELPICCOLO, C. M. L.; ALBERICIO, F.; SCHIKSNIS, R. A.; MICHELOTTI, E. L.
Revista:
TETRAHEDRON
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD.
Referencias:
Lugar: OXFORD (Inglaterra); Año: 2007 vol. 63 p. 8949 - 8953
ISSN:
0040-4020
Resumen:
Cyclization of N-3 substituted 3-thioureidopropanoic acids in isobutyric anhydride at high temperature resulted in the unexpected formation of N-3,N-1-substituted dihydrouracils, as confirmed by thorough spectroscopic characterization. A mechanism based on the identification of intermediates observed at lower reaction temperatures is proposed.
