A partly normalization in the immune-endocrine circulating profile in tuberculosis patients undergoing specific treatment

DIAZ ARIANA; BONGIOVANNI BETTINA; DATTLIO LUCIANO; SANTUCCI NATALIA; DÍDOLI GRISELDA; BRANDAN NADIA; NANNINI LUIS; RADCLIFFE STELLA; BOTTASSO OSCAR; BAY MARÍA LUISA

Milan

Congreso; 15th International Congress of Immunology 2013 (ICI2013); 2013

International Society of Immunology

Tuberculosis (TB) continues to be a global health problem. Extending our earlier findings in which untreated TB patients revealed imbalanced immune-endocrine responses, we have now analyzed the immune-endocrine profile throughout the 6-month course of specific treatment and 3 month following its completion. Twenty healthy controls (HCo) and 19 age- and sex-matched TB -HIV negative- patients were bled at diagnosis (T0), two (T2), four (T4) and 6 months (T6) of treatment as well as 3 months later (T9). At diagnosis patients showed a low BMI (p