INVESTIGADORES
LADERACH Diego Jose
congresos y reuniones científicas
Título:
Hemin treatment potentiates CD8+ T cell proliferation and effector function and impacts upon in vivo prostate cancer progression
Autor/es:
JAWORSKI, FELIPE MARTÍN; GENTILINI, LUCAS DANIEL; GUERON, GERALDINE; COMPAGNO, DANIEL GEORGES; VAZQUEZ, ELBA SUSANA & LADERACH, DIEGO JOSÉ
Lugar:
Buenos Aires
Reunión:
Congreso; Reunión Anual Sociedad Argentina de Inmunología; 2015
Institución organizadora:
Sociedad Argentina de Inmunología
Resumen:
Inflammatory microenvironments have been increasingly recognised as a risk factor for prostate cancer (PCa) and, in this regard, we have previously shown that modulation of inflammation-induced Heme Oxygenase-1 (HO-1) profoundly impacts different aspects of disease progression. The present work focuses on the role of stromal HO-1. Subcutaneous TRAMP-C1 (TC1) tumours growing in syngeneic C57BL/6 mice displayed increased tumour latency (12 days; P
