INVESTIGADORES
ACOSTA RODRIGUEZ Eva Virginia
artículos
Título:
Cytokines and chemokines shaping the B-cell compartment
Autor/es:
ACOSTA RODRIGUEZ EV; MERINO MC; MONTES CL; MOTRAN CC; GRUPPI A
Revista:
CYTOKINE & GROWTH FACTOR REVIEWS
Referencias:
Año: 2007 p. 73 - 83
ISSN:
1359-6101
Resumen:
The whole life of a B-cell from a stem cell to a mature plasma cell is governed, among other factors, by cytokines and growth factors in
their microenvironment. Remarkable progress in the understanding of the mechanisms of cytokines action on the B-cell compartment was
achieved by analysis of gene-targeted mice. The generation of mice deficient for individual cytokines or their receptors has shed light on the in
vivo function of cytokines in B-cell responses. This review focuses on the role of cytokines in the development, maturation and differentiation
of different B-cell subsets into antibody-secreting cells or memory B-cells.
of different B-cell subsets into antibody-secreting cells or memory B-cells.
vivo function of cytokines in B-cell responses. This review focuses on the role of cytokines in the development, maturation and differentiation
of different B-cell subsets into antibody-secreting cells or memory B-cells.
of different B-cell subsets into antibody-secreting cells or memory B-cells.
in
vivo function of cytokines in B-cell responses. This review focuses on the role of cytokines in the development, maturation and differentiation
of different B-cell subsets into antibody-secreting cells or memory B-cells.
of different B-cell subsets into antibody-secreting cells or memory B-cells.
function of cytokines in B-cell responses. This review focuses on the role of cytokines in the development, maturation and differentiation
of different B-cell subsets into antibody-secreting cells or memory B-cells.
