Mechanisms of inhibition of LHRH release by alcohol and cannabinoids

RETTORI, V; LOMNICZI, A; MOHN, C; SCORTICATI, C; VISSIO, P; LASAGA, M; FRANCHI, A; MCCANN, S

Progress in Brain Research

ELSEVIER SCIENCE BV

Lugar: Amsterdam; Año: 2002 vol. 141 p. 177 - 183

0079-6123

This paper will review our research and that of ourassociates on the effects of alcohol and cannabinoidson reproduction. Today, alcohol is classified as apsychotropic drug, like delta-9 tetrahydrocannabinol(THC), the active ingredient of marihuana. A largenumber of neurotransmitters not only the classicalones, but also a host of neuropeptides that can actas neutransmitters or neuromodulators, exist in thecentral nervous system (CNS) and there is abundantevidence that alcohol and cannabinoids can affect anumber of them. Therefore, mechanisms of action ofthese drugs in the CNS are very complex.Addiction to alcohol or marihuana produces