INVESTIGADORES
PARREÑO Gladys Viviana
libros
Título:
The Guinea Pig Model An Alternative Method for Vaccine Potency Testing
Autor/es:
PARREÑO, VIVIANA
Editorial:
CRC Press Taylor & Francis
Referencias:
Lugar: New York; Año: 2023 p. 170
ISSN:
9781032446400
Resumen:
This book summarizes the development and statistical validation of a guinea pig model as an alternative for potency testing of the viral antigens included in combined vaccines applied in cattle to control the respiratory, reproductive, and neonatal calf diarrhea syndromes. The model allows, in one serum sample, to test the vaccine quality for all the viral antigens included in aqueous as well as in oil-adjuvanted formulations of bovine vaccines. The methodology proposed for the control of bovine herpes virus, parainfluenza, and rotavirus were recommended by CAMEVET as guidelines for the 30 countries in the forum, including the US.Key FeaturesReviews combined vaccines used for cattleSummarizes animal models used for vaccine testingFocuses on bovine herpesviruses, rotaviruses, parainfluenza, and bovine viral diarrhea virusProvides guidance on the effectiveness of the Guinea Pig model for testing vaccine immunogenicity
